The rapper was gunned down in a drive-by shooting on September 7
His murder remains one of the biggest unsolved mysteries in the entertainment world... until now.
A new Netflix series, Unsolved: The Tupac And Biggie Murders, contains
One of the most popular theories surrounding Tupac's murder is that he and Death Row Records CEO Suge Knight were involved in the beating of a Crips member, Orlando 'Baby Lane' Anderson, on the night of Pac's death.
And now Anderson's uncle, Keefe D - real name Duane Keith Davis - has confessed that he knew who pulled the trigger that fateful night.
"I was a Compton kingpin, drug dealer, I'm the only one alive who can really tell you story about the Tupac killing," said Keefe D, the Daily Star reports.
"People have been pursuing me for 20 years, I'm coming out now because I have cancer. And I have nothing else to lose. All I care about now is the truth."
Keefe's shocking confession was caught on tape when he had immunity from prosecution, which aired in a different documentary, Death Row Chronicles.
He revealed that he, Anderson and two others - Terrence 'T-Brown' Brown and DeAndre 'Dre' Smith - were in a Cadillac driving around Vegas looking for Tupac on the night of the murder, as revenge for his nephew's beating.
They were on their way to the 662 Club where Tupac was due to
The foursome went to buy
"All the chicks
"If he wouldn't even have been out the window we would have never have seen him."
However, he refused to tell the Death Row Chronicles documentary makers who pulled the trigger.
"Going to keep it for the code of the streets. It just came from the backseat, bro," he said on camera.
However, in the taped confession filmed during his immunity, Keefe said it was his nephew Orlando who fired the gun
"I gave it to Dre and Dre was like 'no, no, no' and Lane was like – popped the dudes," he claimed.
"He leaned over and rolled down the window and popped them."
Anderson himself continued to deny responsibility for Tupac's murder his whole life - he was killed during a shootout in LA in 1998.